Oxybutynin MR (Lyrinel XL)
It is not acceptable for short-term use prior to bladder surgery. Only the sustained-release formulation is permitted.
Tolterodine MR (Detrusitol XL)
Solifenacin (Vesicare)
Darifenacin (Emselex)
Trospium IR and MR (Regurin)
Side-effects to enquire about are mainly anti-cholinergic such as dry mouth, blurred vision and drowsiness. If these do not occur in the first few months they are extremely unlikely to occur later.
Class 1
Unfit for a minimum of four weeks or until a stable dose is achieved with adequate symptom control.
OML for at least four months.
If the dose of drug remains stable with satisfactory symptom control and no reported side-effects, then unrestricted certification can be considered at four months. Any change in dosage should entail a grounding period of four weeks followed by reassessment. Pilots should be advised to keep themselves hydrated before and during flights.
Class 2
Unfit for a minimum of four weeks or until a stable dose to achieve with adequate symptom control. If the dose of drug remains stable with satisfactory symptom control and no reported side-effects, then unrestricted certification can be considered at four weeks. Any change in dosage should entail a grounding period of four weeks, followed by reassessment.
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